Harrison Ford will star in Crowley as a scientist.

Reese Witherspoon and Ben Stiller will combine with Cameron Crowe.

After returning to Indiana Jones this summer Harrison Ford is changing gears and playing a scientist. Variety through Coming Soon say he will star in CBS Films' Crowley. The film is based on a true story, that of John and Aileen Crowley. Their two children had a rare genetic disorder, and John Crowley set about finding a cure. Harrison Ford will star as the scientist who has a potential cure, and he will also be executive producing.

Reese Witherspoon and Ben Stiller will star in a "romantic comedy adventure", written and directed by Cameron Crowe. Variety say filming will begin in January, but plot details are thin on the ground. No doubt we'll hear more soon.